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Principal Investigators

The REPEAT Trial is led by an international group of experts in cardiovascular medicine and clinical trial design.

Principal Investigator UK

Enoch Akowuah

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Dr. Akowuah is an Academic Consultant Cardiothoracic Surgeon at Newcastle University and South Tees NHS Foundation in the United Kingdom.

Principal Investigator Germany

Stefan Blankenberg

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Dr. Blankenberg is the director of the Department of Cardiology at the University Heart & Vascular Center Hamburg, Germany.

International Principal Investigator

Michael A. Borger

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Dr. Borger is the Director of the University Clinic for Cardiac Surgery as well as the Medical

Director of the Leipzig Heart Center in Leipzig, Germany.

Principal Statistician

Marcio Diniz

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Dr. Diniz is a professor at the Department of Population Health Science and Policy, Icahn School of Medicine at Mount Sinai, New York, USA.

Principal Investigator USA

Tsuyoshi Kaneko

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Dr. Kaneko is the director of the Division of Cardiothoracic Surgery at Washington University, St. Louis, USA.

Principal Investigator USA

Raj Makkar

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Dr. Makkar is the Stephen R. Corday Chair in Interventional Cardiology, and Professor of Medicine and Cardiology at UCLA and Cedars-Sinai in Los Angeles, USA.

Principal Investigator Australia

Martin Ng

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Dr. Ng is a physician-scientist and interventional cardiologist, Professor of Cardiovascular Medicine and Bioengineering at the University of Sydney, and a Senior Staff Specialist in Cardiology at Royal Prince Alfred Hospital.

Founding Principal Investigator

Matthias Raschpichler

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Dr. Raschpichler is a cardiac surgeon–scientist and clinical trial leader at the Heart Center Leipzig, Germany.

Clinical Research Organization

The REPEAT Trial is managed by the Helios Health Institute, associated with the Heart Center Leipzig, Germany.

Sabine Spänig

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Sabine Spaenig is the Head of Clinical Trial Management & Real World Data at Helios Health Institute.

Anne Nitsche

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Dr. Nitsche is a Senior Data Scientist at Helios Health Institute. She provides the digital infrastructure of the REPEAT Trial.

Eva Kirchhof

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Eva Kirchhof is a senior project manager at Helios Health Institute. She manages the REPEAT Trial nationally and provides support for the international partners.

Clinical Research Organization

The REPEAT Trial is managed by the Helios Health Institute, associated with the Heart Center Leipzig, Germany.

Sabine Spänig

SabineSpaenig_2986_edited_edited.jpg

Sabine Spaenig is the Head of Clinical Trial Management & Real World Data at Helios Health Institute.

Anne Nitsche

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Dr. Nitsche is a Senior Data Scientist at Helios Health Institute. She provides the digital infrastructure of the REPEAT Trial.

Eva Kirchhof

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Eva Kirchhof is a senior project manager at Helios Health Institute. She manages the REPEAT Trial nationally and provides support for the international partners.

United Kingdom Research Group

The South Tees Academic Cardiovascular Unit manages the REPEAT Trial branch that enrolls patients in the United Kingdom.

Rebecca Maier

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Rebecca Maier is the head of the Academic Cardiovascular Unit, overseeing all trial-related operations in the UK. 

Lisa Chang

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Dr. Chang is a Principal Research Manager at the Academic Cardiovascular Research Unit, ensuring clinical and academic accuracy of the UK trial branch.

Helen Tohill

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Helen Tohill is a Research Coordinator at the Academic Cardiovascular Research Unit, managing the UK trial branch on the national level.

Bioengineering Laboratory Sydney

The REPEAT Trial is collaborating with the University of Sydney to study the processes of valve failure using cutting-edge biomedical research & technology. 

Research Lead

Steven Wise

Dr. Steven Wise, Sydney

Dr. Wise is a Bioengineer, Heart Foundation Future Leader Fellow, and Professor of Cardiovascular Bioengineering at the University of Sydney.

Bioengineering Laboratory
Sydney

The REPEAT Trial is collaborating with the University of Sydney to study the processes of valve failure using cutting-edge biomedical research & technology. 

Research Lead

Steven Wise

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Dr. Wise is a Bioengineer, Heart Foundation Future Leader Fellow and Professor of Cardiovascular Bioengineering at the University of Sydney.

Leipzig, Germany

Heart Center Leipzig

Cardiac Surgery
  • Michael Borger, MD, PhD

  • David Holzhey, MD

  • Thilo Noack, MD

  • Matthias Raschpichler, MD, PhD

  • Ricardo Spampinato, MD

Cardiology
  • Mohamed Abdel-Wahab, MD

  • Hans-Josef Feistritzer, MD

  • Nico Majunke, MD

  • Max Roeder, MD

  • Holger Thiele, MD

Participating Sites

The REPEAT Trial includes recognized cardiovascular units from around the world. 

Heart Center Leipzig

Lead Center Germany

The Heart Center Leipzig in Leipzig, Germany, is the national leading site of the REPEAT Trial and actively enrolling patients. 

Taylor Quill

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Kris Ward

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Morgan James

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